Genentech Initiates First-in-Human Study with NovImmune’s Anti-IL17 Antibody
|| Print ||
|Tuesday, 13 December 2011 09:15 (UTC + 1)|
Plan-Les-Ouates, Geneva, Switzerland, December 13, 2011 / B3C newswire / - NovImmune announced today that Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), initiated a First-in-Human study with anti-IL-17 (NI-1401, RG7624), a fully human monoclonal antibody designed to specifically and selectively bind to the human IL-17 family of cytokines. The anti-IL-17 antibody was generated at NovImmune and licensed to Genentech in July 2010. The initiation of the Phase I clinical trial triggers a milestone payment from Genentech of an undisclosed amount.
Jack Barbut, CEO, commented "With the compound entering man, NovImmune is gratified to see Genentech’s continued commitment to the anti-IL-17 program. This news creates an additional milestone as this is the fifth NovImmune therapeutic antibody to enter clinical development; a significant achievement for a small biotech company."
In addition, NovImmune has developed a proprietary platform for the generation of fully human mono-, bi-- and panspecific antibodies including the κλ body which is a bispecific indistinguishable from an IgG.