Livingston, United Kingdom, October 8, 2012 / B3C newswire / - Encap Drug Delivery (EDD) and the School of Pharmacy, Queen’s University Belfast have received funding from the Technology Strategy Board and the Scottish Government that will allow both to enter into a collaborative Knowledge Transfer Partnership (KTP) on Hot Melt Extrusion (HME).
Encap is a contract development and manufacturing organisation (CDMO) which has pioneered the application of liquid and semi-solid filled hard capsules for pharmaceutical products. For more than 20 years the company has successfully applied the technology to a wide range of client new molecular entities (NMEs) which have required solubility and bioavailability enhancement. Since its inception the company has focused on gaining a sound scientific understanding of the formulation strategies which can be tailored to the individual characteristics of the target molecules and more importantly translating these formulations into scalable and commercial liquid filled pharmaceutical products.
It is the company’s intention to apply a similar strategy to the development of HME products and Encap will differentiate itself from other development services companies by providing a sound scientific understanding of the technology. This will ensure that products are developed on a rigorous scientific basis and promote robust and scalable manufacturing processes which will enable clients to move quickly and efficiently through clinical development to registration and commercialisation.
Dr Jane Fraser said ‘I am delighted to be working with Professor David Jones and Dr Gavin Andrews of QUB which is recognised as a world leader in the field of HME research. Encap is dedicated to providing world-class development and manufacturing services to its global clients and we are confident that we can establish and grow HME as a mainstream technology for poorly soluble molecules. We believe that this will be a valuable addition to the formulator’s tool box and will fit well with our other enabling technologies’.
Dr Gavin Andrews reiterated the importance of the grant programme ‘Specifically, our intention is that QUB will implement a robust, continuous melt extrusion process capable of engineering solid dispersions. In so doing we aim to complement existing soluble enhancement approaches through the addition of HME and thus bolster Encap’s technologies portfolio’
About Encap Drug Delivery
Encap Drug Delivery is the world’s largest contract development and manufacturing organization (CDMO) totally dedicated to liquid and semi-solid (hot melt) filled capsules. The company was established in 1989 and is a global provider of oral drug delivery and pharmaceutical development services. The company provides clients with fully integrated analytical and formulation development services, clinical trial manufacturing and high volume commercial manufacturing. Encap’s state-of-the-art facility in the
For further information please contact:
Leona Dunlop
Encap Drug Delivery
Units 4, 5 & 6,
Tel: +44 (0)1506 448080.
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