Improved Sensitivity with the New Protein and Phospholipid Removal Plate from Biotage
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|Wednesday, 22 January 2014 17:00 (UTC + 1)|
Uppsala, Sweden, January 22, 2014 / B3C newswire / – Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, is pleased to announce the launch of ISOLUTE® PLD+, a protein and phospholipid removal plate for the clean-up of blood based matrix samples for analysis by LC-MS/MS.
ISOLUTE® PLD+ plates combine protein and phospholipid removal in a single product providing very effective and extremely simple sample clean-up for LC-MS/MS analysis. Utilizing our solvent crash / filter process the plates also incorporate a phospholipid scavenging sorbent layer, which removes phospholipids from the sample during the filtration step. ISOLUTE® PLD+ plates remove more than 99% of plasma proteins and phospholipids, the main causes of ion suppression, leading to cleaner extracts and increased sensitivity, signal-to-noise, for a broad range of analytes.
Once purified, samples can be analyzed directly, or evaporated and reconstituted in a solvent that matches your analytical method requirements. ISOLUTE® PLD+ plates can be processed using 96-well compatible positive pressure manifolds (such as the Biotage® Pressure+ 96), vacuum manifolds (for example the Biotage® VacMaster™ 96) and most automated liquid handling systems. ISOLUTE® PLD+ is available in the standard SBS/ANSI standard 96-well plate format and typical sample volumes of 100 to 200 µL can be processed.
“Requiring next to no method development, ISOLUTE® PLD+ can be integrated quickly and easily into routine workflow, increasing productivity and reducing instrument downtime” said Paul Roberts, Analytical Product Manager, Biotage AB, Sweden.
For further information visit www.biotage.com or call: in Europe +46 18 56 57 10, in North America toll free 1 800 446 4752, in Japan +81 422 28 1233, other areas please call +46 18 56 57 10.